Low Dose Naltrexone (LDN)

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What is Low Dose Naltrexone (LDN)

Low Dose Naltrexone (LDN) is a pharmacological treatment involving the use of naltrexone between 1.5mg and 4.5mg to treat health issues related to immune system dysfunction and inflammation. Low Dose Naltrexone offers a promising, low-cost option for managing a range of chronic and autoimmune conditions, leveraging its unique ability to modulate the immune system and reduce inflammation. Compounding pharmacies are essential in making LDN therapy accessible, providing customized dosing and formulations to meet the diverse needs of patients exploring this treatment avenue. As with any medication or treatment, patients interested in LDN should consult with their healthcare provider to discuss its potential benefits and suitability for their specific health situation.​

What is low dose LDN used to treat?

  • Autoimmune Diseases: Including multiple sclerosis (MS), rheumatoid arthritis, Crohn’s disease, and lupus, where LDN is thought to modulate the immune system and reduce inflammation.​
  • Chronic Pain Disorders: Such as fibromyalgia and chronic regional pain syndrome (CRPS), where LDN may help reduce pain sensitivity.​
  • Inflammatory Skin Conditions: Like eczema and psoriasis, where LDN can help manage inflammation and autoimmune responses affecting the skin.​
  • Thyroid Disorders: Particularly Hashimoto’s thyroiditis, an autoimmune condition affecting the thyroid gland, where LDN can help regulate immune function.​
  • Cancer: Some preliminary studies suggest that LDN could play a role in cancer treatment by boosting the immune response, though more research is necessary.

What is Naltrexone?

Naltrexone itself is a medication approved by the FDA at higher doses (50mg or more) for the treatment of opioid addiction and alcohol dependence. When used at lower doses, typically between 1.5mg and 4.5mg, it’s referred to as Low Dose Naltrexone (LDN). At these lower doses, naltrexone has been found to modulate the immune system and reduce inflammation, making it a subject of interest for treating various autoimmune diseases and chronic pain conditions.