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What is Acne?

Acne is a common skin condition characterized by the occurrence of pimples, blackheads, whiteheads, and sometimes more severe forms such as cysts and nodules. It primarily affects areas of the skin with a high density of oil glands, including the face, back, and chest. From the perspective of medical compounding, acne is not just a surface-level skin disorder but a complex condition that can be influenced by various factors including hormonal fluctuations, genetics, diet, stress levels, and the use of certain medications.

How can a Compounding Pharmacy Help with Acne Treatments?

In compounded acne treatments, active acne treatment ingredients can be combined in customized formulations tailored to the specific needs and skin conditions of the patient. For example, a compounded cream might include both tretinoin for its retinoid benefits and niacinamide for its anti-inflammatory effects, alongside clindamycin to target bacterial growth. The concentration of each ingredient can be adjusted based on the patient’s tolerance and the severity of their acne, allowing for a personalized approach to acne management.

What are the Active Ingredients in VPharmacy’s Compounding Treatments for Acne?

A variety of active ingredients, each targeting different aspects of acne pathology, such as inflammation, bacterial growth, and cell turnover. At VPharmacy, our active ingredients for acne include tretinoin, benzoyl peroxide, niacinamide, adapalene, clindamycin, and azelaic acid for custom compounded formulations for the treatment of acne.


An antibacterial and peeling agent that helps to clear acne by reducing bacteria and removing dead skin cells. It can be compounded into customized concentrations.


Tretinoin is a retinoid, derived from Vitamin A, known for its ability to promote cell turnover and prevent the clogging of pores, which can lead to acne. It also improves skin texture and can reduce the appearance of post-acne scars and hyperpigmentation.


Niacinamide, or Vitamin B3, has anti-inflammatory properties that can reduce the redness and swelling associated with acne. It is also known for its ability to strengthen the skin’s barrier function, reduce sebum production, and improve skin texture.


Adapalene is a third-generation retinoid primarily used in the treatment of acne. It works similarly to tretinoin but is regarded as more stable and less irritating. Adapalene promotes cell turnover and prevents the formation of comedones.


Clindamycin is an antibiotic that fights bacteria associated with acne, When used topically, clindamycin can reduce the number of bacterial colonies and decrease inflammation.


Azelaic acid is a dicarboxylic acid that has antimicrobial, anti-inflammatory, and comedolytic properties. It is effective in treating mild to moderate acne and is particularly useful for patients with sensitive skin or those who cannot tolerate other treatments.

Dermatology practices and medical spas (medspas) frequently encounter patients with unique skin care needs and concerns that off-the-shelf products may not adequately address. The collaboration between dermatology practices, medspas, and VPharmacy enriches the range of treatment options available to patients, offering tailored solutions that address the root of skin care challenges. This partnership leverages the strengths of both professionals, combining clinical expertise with formulation skills to enhance patient care, satisfaction, and outcomes in dermatological treatment and aesthetic enhancement.